M.Sc. (Hons. School) in Biochemistry (Panjab University, Chandigarh)
Ph.D. in Biotechnology (Panjab University, Chandigarh)
Raman Fellowship (Post Doctorate Fellowship) from Texas Tech University Health Sciences Center, Lubbock TX USA
Teaching and research Experience at national and international institutions
- Professor of Molecular Medicine, Central University of Punjab Bathinda India (Jan 2023-onward)
- Associate Professor, Central University of Punjab Bathinda India (Jan 2020-23)
- Raman Post Doc Fellow, Texas Tech University Health Sciences Centre, Lubbock, Texas USA (Aug 2016-17)
- Research Scientist, Department of Biochemistry at Panjab University Chandigarh (May 2015-16)
- Assistant Professor, Sri Guru Gobind Singh College, Chandigarh India (July 2007 to Jan 2020)
Administrative Experience:
- Head, Department of Human Genetics & Molecular Medicine, Central University of Punjab, Bathinda India (4th March 2020 to 10th Mar, 2023)
- Associate Dean, School of Health Sciences, Central University of Punjab, Bathinda India (4th June – 16th Nov 2020)
- Academic Council Member, Central University of Punjab, Bathinda India (28th May 2020 onward)
- NSS Program Officer (Sept 2018 - April 2019)
- Coordinator, NAAC & IQAC (2009-2011)
- Coordinator, Grants Cell (2009- 2011)
- Coordinator, Environment Society (2009-2010)
- Coordinator, Red Ribbon Club (2009-2011)
- Coordinator, IGNOU Study Centre-06007 (Nov 2012- Dec 2014)
- Epidemiological Studies, Pharmacogenomics of Type 2 Diabetes and Coronary Artery Disease
- Molecular mechanisms underlying the pathogenesis of age-associated metabolic and neurodegenerative diseases
- Nanotherapeutics
- Molecular Toxicology of organophosphates and heavy metals
- Mitochondria-targeted therapeutic strategies in Neurodegenerative diseases
- Study models: Human/Rats/Mice/Cell Lines/Stem cells.
My research endeavors aim to unravel the molecular underpinnings of the pathogenesis of age-related diseases, such as type 2 diabetes mellitus (T2DM), coronary artery disease (CAD), Cancer, and neurological disorders, utilizing both human subjects and rodent models. I possess a profound interest in exploring the genetic underpinnings of T2DM, CAD, Cancer, and Alzheimer's Disease; the potential of mitochondria-focused treatments; and the applications of nanomedicine, all through the utilization of state-of-the-art, high-throughput methodologies. My research laboratory "Laboratory of Translational Medicine and Nanotherapeutics" complemented by a fully-equipped instrumentation facility, is adept at conducting research spanning cellular, molecular, and genomic analyses of diverse diseases. My current PhD students are directed towards pinpointing novel molecular targets for integration into clinical settings as viable diagnostic or therapeutic biomarkers, particularly for conditions such as Myocardial Infarction, Diabetic Nephropathy, and the nano-delivery of drugs targeting neurodegenerative diseases.
- 2020-23: SERB Project (Rs. 50.50 lacs)
- 2021-24: SERB-TARE project as mentor (Rs. 18.30 Lacs)
- 2016-17: Raman Post Doctoral Research Award in USA
- 2015-16: UGC Research Award
- 2011-14: UGC Funded Major Research Project (Rs. 14.97 Lacs)
- Life Member - The Indian Science Congress Association, India (L31752/2017)
- Life Member - Punjab Academy of Sciences, India (L/1429/2017)
- Life Member - Indian Society for Clinical Research, India (874/2017)
- Life Member - Society for Mitochondria Research and Medicine, India (L/151/2015)
- Life Member - Indian Academy of Neurosciences (IAN), India (LB – 81, 2016)
- Life Member - Alzheimer’s and Related Disorders Society of India (377/2016)
- Life Member - Indian Society of Human Genetics, India (L/1646/2012)
- Life Member –CRIKC (Chandigarh Region Innovation and Knowledge Cluster) Society India (2018)
- Annual Member-Society for Neurosciences, USA 2017 (ID: 210962008/2017)
Central University of Punjab Research Award for publication of papers as a Co-author achieving a cumulative Impact Factor >15 for the year 2020-21.
Central University of Punjab Research Award for publication of a single paper as the First/Corresponding Author, with an Impact Factor >12 for the year 2022-23.
Central University of Punjab Research Award for publication of a paper as the First/Corresponding Author, achieving a cumulative Impact Factor >24 for the year 2022-23.
Central University of Punjab Research Award for contribution to co-authored papers, resulting in a cumulative Impact Factor >36 for the year 2022-23.
Central University of Punjab Research Award for Co-authorship of a paper published in a journal with an Impact Factor >50, notably including a contribution to a paper in Lancet with an IF of 169.
UGC Research Award to serve/conduct research at an institute of national importance, funded by University Grants Commission, Govt. of India for a period of 2 years (2014-16).
Raman Post Doctoral Fellow in USA for a period of 1 year (Aug 2016-17) under the prestigious "Raman Award" funded by University Grants Commission, Govt. of India.
- Texas Tech University Health Sciences Center, Lubbock TX USA
- Genetics Research Lab, University of Loughborough, Loughborough UK
- Department of Cardiology, and Endocrinology, PGIMER, Chandigarh India
- Department of Biochemistry, Govt Medical College and Hospital, Patiala, Punjab India
- All India Institute of Medical Sciences, Bathinda, India
- Chandigarh University Mohali Punjab India
- Lovely Professional University Phagwara Punjab India
- Amity University Jaipur, Rajasthan India
Google Scholar: https://scholar.google.co.in/citations?user=VnblK8EAAAAJ&hl=en
Publication Details
1. Patel D, Yadav P, Singh SK, Tanwar SS, Sehrawat A, Khurana A, et al. Betaine alleviates doxorubicin-induced nephrotoxicity by preventing oxidative insults, inflammation, and fibrosis through the modulation of Nrf2/HO-1/NLRP3 and TGF-beta expression. J Biochem Mol Toxicol. 2024;38(1):e23559. doi: 10.1002/jbt.23559 (Impact Factor 3.6).
2. Missong H, Joshi R, Khullar N, Thareja S, Navik U, Bhatti GK, et al. Nutrient-epigenome interactions: Implications for personalized nutrition against aging-associated diseases. J Nutr Biochem. 2024;127:109592. doi: 10.1016/j.jnutbio.2024.109592 (Impact Factor 5.6).
3. Pesudovs K, Lansingh VC, Kempen JH, Tapply I, Fernandes AG, Cicinelli MV, et al. Global estimates on the number of people blind or visually impaired by cataract: a meta-analysis from 2000 to 2020. Eye (Lond). 2024. doi: 10.1038/s41433-024-02961-1 (Impact Factor 3.9).
4. Mahato RK, Bhattacharya S, Khullar N, Sidhu IS, Reddy PH, Bhatti GK, et al. Targeting long non-coding RNAs in cancer therapy using CRISPR-Cas9 technology: A novel paradigm for precision oncology. J Biotechnol. 2024;379:98-119. doi: 10.1016/j.jbiotec.2023.12.003. (Impact Factor 5.0).
5. Kumari S, Raj S, Babu MA, Bhatti GK, Bhatti JS. Antibody-drug conjugates in cancer therapy: innovations, challenges, and future directions. Arch Pharm Res. 2024;47(1):40-65. doi: 10.1007/s12272-023-01479-6. (Impact Factor 6.7).
6. Fertility GBD, Forecasting C. Global fertility in 204 countries and territories, 1950-2021, with forecasts to 2100: a comprehensive demographic analysis for the Global Burden of Disease Study 2021. Lancet. 2024. doi: 10.1016/S0140-6736(24)00550-6. (Impact Factor 168.9).
7. Collaborators GBDT. Global, regional, and national age-specific progress towards the 2020 milestones of the WHO End TB Strategy: a systematic analysis for the Global Burden of Disease Study 2021. Lancet Infect Dis. 2024. doi: 10.1016/S1473-3099(24)00007-0. (Impact Factor 56.3).
8. Collaborators GBDNSD. Global, regional, and national burden of disorders affecting the nervous system, 1990-2021: a systematic analysis for the Global Burden of Disease Study 2021. Lancet Neurol. 2024;23(4):344-81. doi: 10.1016/S1474-4422(24)00038-3. (Impact Factor 48.0).
9. Collaborators GBDD. Global age-sex-specific mortality, life expectancy, and population estimates in 204 countries and territories and 811 subnational locations, 1950-2021, and the impact of the COVID-19 pandemic: a comprehensive demographic analysis for the Global Burden of Disease Study 2021. Lancet. 2024. doi: 10.1016/S0140-6736(24)00476-8. (Impact Factor 168.9).
10. Ajmera H, Lakhawat SS, Malik N, Kumar A, Bhatti JS, Kumar V, et al. Global Emergence of SARS-CoV2 Infection and Scientific Interventions to Contain its Spread. Curr Protein Pept Sci. 2024. doi: 10.2174/0113892037274719231212044235. (Impact Factor 2.8).
11. Verma A, Yadav P, Rajput S, Verma S, Arora S, Kumar R, et al. ALK and ERBB2 Protein Inhibition is Involved in the Prevention of Lung Cancer Development by Vincamine. Anticancer Agents Med Chem. 2023;23(13):1587-95. doi: 10.2174/1871520623666230412102532. (Impact Factor 2.8).
12. Sharma G, Biswas SS, Mishra J, Navik U, Kandimalla R, Reddy PH, et al. Gut microbiota dysbiosis and Huntington's disease: Exploring the gut-brain axis and novel microbiota-based interventions. Life Sci. 2023;328:121882. doi: 10.1016/j.lfs.2023.121882. (Impact Factor 6.1).
13. Sharma A, Arya SK, Singh J, Kapoor B, Bhatti JS, Suttee A, et al. Prospects of chitinase in sustainable farming and modern biotechnology: an update on recent progress and challenges. Biotechnol Genet Eng Rev. 2023:1-31. doi: 10.1080/02648725.2023.2183593. (Impact Factor 3.2).
14. Sehrawat A, Mishra J, Mastana SS, Navik U, Bhatti GK, Reddy PH, et al. Dysregulated autophagy: A key player in the pathophysiology of type 2 diabetes and its complications. Biochim Biophys Acta Mol Basis Dis. 2023;1869(4):166666. doi: 10.1016/j.bbadis.2023.166666. (Impact Factor 6.2).
15. Sardana Y, Bhatti GK, Singh C, Sharma PK, Reddy PH, Bhatti JS. Progression of pre-rheumatoid arthritis to clinical disease of joints: Potential role of mesenchymal stem cells. Life Sci. 2023;321:121641. doi: 10.1016/j.lfs.2023.121641. (Impact Factor 6.1).
16. Mukherjee S, Bhatti GK, Chhabra R, Reddy PH, Bhatti JS. Targeting mitochondria as a potential therapeutic strategy against chemoresistance in cancer. Biomed Pharmacother. 2023;160:114398. doi: 10.1016/j.biopha.2023.114398. (Impact Factor 7.5).
17. Mensah GA, Fuster V, Murray CJL, Roth GA, Global Burden of Cardiovascular D, Risks C. Global Burden of Cardiovascular Diseases and Risks, 1990-2022. J Am Coll Cardiol. 2023;82(25):2350-473. doi: 10.1016/j.jacc.2023.11.007. (Impact Factor 24.0).
18. Kumar S, Senapati S, Bhattacharya N, Bhattacharya A, Maurya SK, Husain H, et al. Mechanism and recent updates on insulin-related disorders. World J Clin Cases. 2023;11(25):5840-56. doi: 10.12998/wjcc.v11.i25.5840. (Impact Factor 1.1).
19. Khullar N, Bhatti JS, Singh S, Thukral B, Reddy PH, Bhatti GK. Insight into the liver dysfunction in COVID-19 patients: Molecular mechanisms and possible therapeutic strategies. World J Gastroenterol. 2023;29(14):2064-77. doi: 10.3748/wjg.v29.i14.2064. (Impact Factor 4.3).
20. Kaur S, Sehrawat A, Mastana SS, Kandimalla R, Sharma PK, Bhatti GK, et al. Targeting calcium homeostasis and impaired inter-organelle crosstalk as a potential therapeutic approach in Parkinson's disease. Life Sci. 2023;330:121995. doi: 10.1016/j.lfs.2023.121995. (Impact Factor 6.1).
21. Ghosh S, Bhatti GK, Sharma PK, Kandimalla R, Mastana SS, Bhatti JS. Potential of Nano-Engineered Stem Cells in the Treatment of Multiple Sclerosis: A Comprehensive Review. Cell Mol Neurobiol. 2023;44(1):6. doi: 10.1007/s10571-023-01434-5. (Impact Factor 4.0 ).
22. Ghosh N, Chacko L, Vallamkondu J, Banerjee T, Sarkar C, Singh B, et al. Clinical Strategies and Therapeutics for Human Monkeypox Virus: A Revised Perspective on Recent Outbreaks. Viruses. 2023;15(7). doi: 10.3390/v15071533. (Impact Factor 4.7).
23. Dhapola R, Sharma P, Kumari S, Bhatti JS, HariKrishnaReddy D. Environmental Toxins and Alzheimer's Disease: a Comprehensive Analysis of Pathogenic Mechanisms and Therapeutic Modulation. Mol Neurobiol. 2023. doi: 10.1007/s12035-023-03805-x. (Impact Factor 5.1 ).
24. Collaborators GBDD. Global, regional, and national burden of diabetes from 1990 to 2021, with projections of prevalence to 2050: a systematic analysis for the Global Burden of Disease Study 2021. Lancet. 2023;402(10397):203-34. doi: 10.1016/S0140-6736(23)01301-6. (Impact Factor 168.9).
25. Bhatti JS, Khullar N, Vijayvergiya R, Navik U, Bhatti GK, Reddy PH. Mitochondrial miRNA as epigenomic signatures: Visualizing aging-associated heart diseases through a new lens. Ageing Res Rev. 2023;86:101882. doi: 10.1016/j.arr.2023.101882. (Impact Factor 13.1).
26. Bhatti JS, Khullar N, Mishra J, Kaur S, Sehrawat A, Sharma E, et al. Stem cells in the treatment of Alzheimer's disease - Promises and pitfalls. Biochim Biophys Acta Mol Basis Dis. 2023;1869(6):166712. doi: 10.1016/j.bbadis.2023.166712. (Impact Factor 6.2).
27. Bhatti JS, Kaur S, Mishra J, Dibbanti H, Singh A, Reddy AP, et al. Targeting dynamin-related protein-1 as a potential therapeutic approach for mitochondrial dysfunction in Alzheimer's disease. Biochim Biophys Acta Mol Basis Dis. 2023;1869(7):166798. doi: 10.1016/j.bbadis.2023.166798. (Impact Factor 6.2).
28. Bhattacharya S, Mahato RK, Singh S, Bhatti GK, Mastana SS, Bhatti JS. Advances and challenges in thyroid cancer: The interplay of genetic modulators, targeted therapies, and AI-driven approaches. Life Sci. 2023;332:122110. doi: 10.1016/j.lfs.2023.122110. (Impact Factor 6.1).
29. Beaumont R, Akam L, Singh P, Bhatti JS, Mastana S. Genomic diversity and differentiation of Alu insertion polymorphisms in a native British and four South Asian migrant populations. Ann Hum Biol. 2023;50(1):117-22. doi: 10.1080/03014460.2023.2180091. (Impact Factor 1.7).
30. Abdul Rahman SM, Bhatti JS, Thareja S, Monga V. Current development of 1,2,3-triazole derived potential antimalarial scaffolds: Structure- activity relationship (SAR) and bioactive compounds. Eur J Med Chem. 2023;259:115699. doi: 10.1016/j.ejmech.2023.115699. (Impact Factor 6.7).
31. Yadav P, Sarode LP, Gaddam RR, Kumar P, Bhatti JS, Khurana A, et al. Zebrafish as an emerging tool for drug discovery and development for thyroid diseases. Fish Shellfish Immunol. 2022;130:53-60. doi: 10.1016/j.fsi.2022.09.001. (Impact Factor 4.7).
32. Yadav P, Khurana A, Bhatti JS, Weiskirchen R, Navik U. Glucagon-like peptide 1 and fibroblast growth factor-21 in non-alcoholic steatohepatitis: An experimental to clinical perspective. Pharmacol Res. 2022;184:106426. doi: 10.1016/j.phrs.2022.106426. (Impact Factor 9.3).
33. Rakshit A, Verma A, Verma S, Bhatti GK, Khurana A, Bhatti JS, et al. Microbiome in Pulmonary Tuberculosis. Microbiome in Inflammatory Lung Diseases. Springer; 2022. p. 167-205.
34. Mishra J, Bhatti GK, Sehrawat A, Singh C, Singh A, Reddy AP, et al. Modulating autophagy and mitophagy as a promising therapeutic approach in neurodegenerative disorders. Life Sci. 2022;311(Pt A):121153. doi: 10.1016/j.lfs.2022.121153. (Impact Factor 6.1 ).
35. Bhatti JS, Sehrawat A, Mishra J, Sidhu IS, Navik U, Khullar N, et al. Oxidative stress in the pathophysiology of type 2 diabetes and related complications: Current therapeutics strategies and future perspectives. Free Radic Biol Med. 2022;184:114-34. doi: 10.1016/j.freeradbiomed.2022.03.019. (Impact Factor 7.4).
36. Bhatti GK, Gupta A, Pahwa P, Khullar N, Singh S, Navik U, et al. Targeting mitochondrial bioenergetics as a promising therapeutic strategy in metabolic and neurodegenerative diseases. Biomed J. 2022;45(5):733-48. doi: 10.1016/j.bj.2022.05.002. (Impact Factor 5.5).
37. Sethi N, Gupta P, Bhatti JS, Priyanka K. Evaluation of phytochemicals and anti-nutritional profile in underutilised green leafy vegetables. European Journal of Molecular & Clinical Medicine. 2021;8(2):443-55.
38. Rawat PS, Jaiswal A, Khurana A, Bhatti JS, Navik U. Doxorubicin-induced cardiotoxicity: An update on the molecular mechanism and novel therapeutic strategies for effective management. Biomed Pharmacother. 2021;139:111708. doi: 10.1016/j.biopha.2021.111708. (Impact Factor 7.4).
39. Navik U, Sheth VG, Khurana A, Jawalekar SS, Allawadhi P, Gaddam RR, et al. Methionine as a double-edged sword in health and disease: Current perspective and future challenges. Ageing Res Rev. 2021;72:101500. doi: 10.1016/j.arr.2021.101500. (Impact Factor 13.1).
40. Bhatti JS, Thamarai K, Kandimalla R, Manczak M, Yin X, Kumar S, et al. Mitochondria-Targeted Small Peptide, SS31 Ameliorates Diabetes Induced Mitochondrial Dynamics in Male TallyHO/JngJ Mice. Mol Neurobiol. 2021;58(2):795-808. doi: 10.1007/s12035-020-02142-7. (Impact Factor 5.1).
41. Bhatti JS, Tamarai K, Kandimalla R, Manczak M, Yin X, Ramasubramanian B, et al. Protective effects of a mitochondria-targeted small peptide SS31 against hyperglycemia-induced mitochondrial abnormalities in the liver tissues of diabetic mice, Tallyho/JngJ mice. Mitochondrion. 2021;58:49-58. doi: 10.1016/j.mito.2021.02.007. (Impact Factor 4.4).
42. Bhatti JS, Tamarai K, Kandimalla R, Manczak M, Yin X, Ramasubramanian B, et al. Mitochondrial Dysfunctioning Induced by Hyperglycemia in the Liver Tissues of Diabetic Mice, TALLYHO/JngJ Strain and Ameliorative Action of a Small Peptide, SS31. Metabolism-Clinical and Experimental. 2021;116. (Impact Factor 9.8).
43. Bhatti JS, Pahwa P, Reddy PH, Bhatti GK. Impaired mitochondrial bioenergetics and signaling pathways: an overview. Clinical Bioenergetics. 2021:61-79.
44. Bhatti JS, Pahwa P, Reddy PH, Bhatti GK. Chapter 2 - Impaired mitochondrial bioenergetics and signaling pathways: an overview. In: Ostojic S, editor. Clinical Bioenergetics. Academic Press; 2021. p. 61-79.
45. Bhatti GK, Pahwa P, Gupta A, Sidhu IS, Navik US, Reddy PH, et al. Targeting Mitochondria as a Novel Disease-Modifying Therapeutic Strategy in Cancer. In: Chakraborti S, editor. Handbook of Oxidative Stress in Cancer: Therapeutic Aspects. Singapore: Springer Singapore; 2021. p. 1-20.
46. Bhatti GK, Pahwa P, Gupta A, Navik U, Bhatti JS. Therapeutic Strategies Targeting Signaling Pathways in Lung Cancer. Targeting Cellular Signalling Pathways in Lung Diseases. Springer; 2021. p. 217-39.
47. Bhatti GK, Khurana A, Garabadu D, Gupta P, Jawalekar SS, Bhatti JS, et al. Various Cellular and Molecular Axis Involved in the Pathogenesis of Asthma. Targeting Cellular Signalling Pathways in Lung Diseases. Springer; 2021. p. 53-95.
48. Bhatti GK, Khullar N, Sidhu IS, Navik US, Reddy AP, Reddy PH, et al. Emerging role of non-coding RNA in health and disease. Metab Brain Dis. 2021;36(6):1119-34. doi: 10.1007/s11011-021-00739-y. (Impact Factor 3.6).
49. Bhatti GK, Kaur N, Bhadada SK, Mastana SS, Singh S, Bhatti JS. Genetic Variants In Adiponectin Gene (+45T/G And +276G/T) and Their Predisposition To Type 2 Diabetes Mellitus in Asian Indian Population. Metabolism. 2021;116:154609. doi: https://doi.org/10.1016/j.metabol.2020.154609. (Impact Factor 9.8).
50. Bhatti GK, Gupta A, Reddy PH, Bhatti JS. Translation of bioenergetics therapies: challenges from bench to bedside. Clinical Bioenergetics. 2021:489-507.
51. Bhatti GK, Gupta A, Reddy PH, Bhatti JS. Chapter 22 - Translation of bioenergetics therapies: challenges from bench to bedside. In: Ostojic S, editor. Clinical Bioenergetics. Academic Press; 2021. p. 489-507.
52. Kaur N, Bhatti GK, Kaur S, Bhadada SK, Singh S, Bhatti JS. Transcription factor 7-like 2 gene, rs12255372 (G/T) variant and susceptibility to type 2 diabetes mellitus in North Indians. Gene Reports. 2020;19:100595.
53. Brearley EJ, Singh P, Bhatti JS, Mastana S. Genetic variation and differentiation among a native British and five migrant South Asian populations of the East Midlands (UK) based on CODIS forensic STR loci. Annals of Human Biology. 2020;47(6):572-83. (Impact Factor 1.7).
54. Bhatti JS, Thamarai K, Kandimalla R, Manczak M, Yin X, Kumar S, et al. Mitochondria-Targeted Small Peptide, SS31 Ameliorates Diabetes Induced Mitochondrial Dynamics in Male TallyHO/JngJ Mice. Mol Neurobiol. 2020. doi: 10.1007/s12035-020-02142-7. (Impact Factor 5.1).
55. Bhatti JS, Bhatti GK, Khullar N, Reddy AP, Reddy PH. Therapeutic strategies in the development of anti-viral drugs and vaccines against SARS-CoV-2 infection. Molecular neurobiology. 2020;57(11):4856-77. (Impact Factor 5.1).
56. Bhatti GK, Reddy AP, Reddy PH, Bhatti JS. Lifestyle modifications and nutritional interventions in aging-associated cognitive decline and Alzheimer’s disease. Frontiers in Aging Neuroscience. 2020;11:369. (Impact Factor 4.8).
57. Tamarai K, Bhatti JS, Reddy PH. Molecular and cellular bases of diabetes: Focus on type 2 diabetes mouse model-TallyHo. Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease. 2019;1865(9):2276-84.
58. Kow M, Akam E, Singh P, Singh M, Cox N, Bhatti JS, et al. Vitamin D receptor (VDR) gene polymorphism and osteoporosis risk in White British men. Annals of Human Biology. 2019;46(5):430-3.
59. Kaur N, Bhatti GK, Bhadada SK, Singh S, Bhatti JS. Association of cholesteryl ester transfer protein gene, TaqIB polymorphism with the risk of type 2 diabetes mellitus in North Indian population. International Journal of Research and Analytical Reviews. 2019;6(1):797-808.
60. Kaur N, Bhatti GK, Bhadada SK, Singh S, Bhatti JS. Genetic susceptibility of transcription factor 7-like 2 gene variant and risk of type 2 diabetes in Asian Indians. Asian Journal of Pharmaceutical and Clinical Research 2019;12(5):151-5. doi: 10.22159/ajpcr.2019.v12i5.33130.
61. Bhatti JS, Vijayvergiya R, Singh B, Bhatti GK. Exosome nanocarriers: A natural, novel, and perspective approach in drug delivery system. Nanoarchitectonics in Biomedicine. Elsevier; 2019. p. 189-218.
62. Bhatti JS, Vijayvergiya R, Singh B, Bhatti GK. Chapter 7 - Exosome nanocarriers: A natural, novel, and perspective approach in drug delivery system. In: Grumezescu AM, editor. Nanoarchitectonics in Biomedicine. William Andrew Publishing; 2019. p. 189-218.
63. Sharma R, Mehta K, Bhatti JS, Mastana S, Singh M, Singh P. Prevalence and Predictors of Age Related Macular Degeneration in the Population of Punjab: North Indian Age Related Macular Degeneration Epidemiology and Molecular Genetic Study (NI-ARMEMS). International Journal of Health Sciences & Research. 2018;8(10):1-8.
64. Saini RK, Sanyal SN, Bhatti JS. Chemopreventive action of non-steroidal anti-inflammatory drugs in 9, 10-dimethylbenzanthracene induced lung carcinogenesis in BALB/C mice: Expression of COX-1, COX-2 and Nf-κB. Journal of Applied Biomedicine. 2018;16(4):320-7.
65. Reddy PH, Manczak M, Yin X, Grady MC, Mitchell A, Tonk S, et al. Protective effects of Indian spice curcumin against amyloid-β in Alzheimer’s disease. Journal of Alzheimer's Disease. 2018;61(3):843-66.
66. Raj R, Navis S, Bhatti JS, Bhadada SK, Ramteke PW. Analysis of complicating risk factors for Type 2 Diabetes Mellitus (T2DM). Integrative Obesity and Diabetes. 2018;4(1):1-5. doi: 10.15761/IOD.1000202.
67. Mehta K, Sharma R, Bhatti JS, Mastana S, Singh M, Singh P. Prevalence and Predictors of Diabetic Retinopathy in the Population of Punjab: North Indian Diabetic Retinopathy Epidemiology and Molecular Genetic Study (Ni-Dreams). International Journal of Health Sciences and Research 2018;8(9):1-9.
68. Kumar M, Singh G, Arya SK, Bhatti JS, Sharma P. Artificial Neuro-Fuzzy Inference System (ANFIS) based validation of laccase production using RSM model. Biocatalysis and Agricultural Biotechnology. 2018;14:235-40.
69. Kaur S, Bhatti GK, Vijayvergiya R, Singh P, Mastana SS, Tewari R, et al. Paraoxonase 1 Gene Polymorphisms (Q192R and L55M) Are Associated with Coronary Artery Disease Susceptibility in Asian Indians. Dubai Diabetes and Endocrinology Journal. 2018;24(1-4):38-47. doi: 10.1159/000494508.
70. Bhatti JS, Vijayvergiya R, Singh B, Bhatti GK. Genetic susceptibility of glutathione S-transferase genes (GSTM1/T1 and P1) to coronary artery disease in Asian Indians. Ann Hum Genet. 2018;82(6):448-56. doi: 10.1111/ahg.12274.
71. Bhatti GK, Kaur S, Vijayvergiya R, Bhadada SK, Mastana SS, Singh B, et al. ENPP1 K121Q functional variant enhances susceptibility to insulin resistance and dyslipidemia with metabolic syndrome in Asian Indians. Dubai Diabetes and Endocrinology Journal. 2018;21(1-4):8-15.
72. Vijayan M, Kumar S, Bhatti JS, Reddy PH. Chapter Four - Molecular Links and Biomarkers of Stroke, Vascular Dementia, and Alzheimer's Disease. In: Reddy PH, editor. Progress in Molecular Biology and Translational Science. Academic Press; 2017. p. 95-126.
73. Vijayan M, Kumar S, Bhatti J, Reddy P. Molecular links and biomarkers of stroke, vascular dementia, and Alzheimer's disease. Progress in molecular biology and translational science. 2017;146:95-126.
74. Reddy PH, Williams J, Smith F, Bhatti JS, Kumar S, Vijayan M, et al. Chapter Five - MicroRNAs, Aging, Cellular Senescence, and Alzheimer's Disease. In: Reddy PH, editor. Progress in Molecular Biology and Translational Science. Academic Press; 2017. p. 127-71.
75. Reddy P, Williams J, Smith F, Bhatti J, Kumar S, Vijayan M, et al. MicroRNAs, aging, cellular senescence, and Alzheimer's disease. Progress in molecular biology and translational science. 2017;146:127-71.
76. Raj R, Bhatti JS, Bhadada SK, Ramteke PW. Association of polymorphisms of peroxisome proliferator activated receptors in early and late onset of type 2 diabetes mellitus. Diabetes & Metabolic Syndrome: Clinical Research & Reviews. 2017;11:S287-S93.
77. Mastana SS, Bhatti JS, Singh P, Wiles A, Holland J. Genetic variation of MHC Class I polymorphic Alu insertions (POALINs) in three sub-populations of the East Midlands, UK. Annals of Human Biology. 2017;44(6):562-7.
78. Kumar S, Vijayan M, Bhatti JS, Reddy PH. Chapter Three - MicroRNAs as Peripheral Biomarkers in Aging and Age-Related Diseases. In: Reddy PH, editor. Progress in Molecular Biology and Translational Science. Academic Press; 2017. p. 47-94.
79. Kumar S, Vijayan M, Bhatti J, Reddy P. MicroRNAs as peripheral biomarkers in aging and age-related diseases. Progress in molecular biology and translational science. 2017;146:47-94.
80. Doody NE, Dowejko MM, Akam EC, Cox NJ, Bhatti JS, Singh P, et al. The Role of TLR4, TNF‐α and IL‐1β in Type 2 Diabetes Mellitus Development within a North Indian Population. Annals of human genetics. 2017;81(4):141-6.
81. Bhatti JS, Bhatti GK, Reddy PH. Mitochondrial dysfunction and oxidative stress in metabolic disorders—A step towards mitochondria based therapeutic strategies. Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease. 2017;1863(5):1066-77.
82. Bhatti J, Kumar S, Vijayan M, Bhatti G, Reddy P. Therapeutic strategies for mitochondrial dysfunction and oxidative stress in age-related metabolic disorders. Progress in molecular biology and translational science. 2017;146:13-46.
83. Bhatti G, Bhatti J, Vijayvergiya R, Singh B. Implications of ACE (I/D) gene variants to the genetic susceptibility of coronary artery disease in Asian Indians. Indian Journal of Clinical Biochemistry. 2017;32(2):163-70.
84. Kaur S, Bhatti GK, Saini NK, Vijayvergiya R, Tewari R, Bhatti JS. Cardiometabolic risk factors associated with coronary artery disease in Asian Indian population. . Journal of Innovations in Pharmaceuticals and Biological Sciences. 2016;3(3):160-75.
85. Bhatti GK, Bhadada SK, Vijayvergiya R, Mastana SS, Bhatti JS. Metabolic syndrome and risk of major coronary events among the urban diabetic patients: North Indian Diabetes and Cardiovascular Disease Study—NIDCVD-2. Journal of Diabetes and its Complications. 2016;30(1):72-8.
86. Raj R, Bhatti JS, Badada SK, Ramteke PW. Genetic basis of dyslipidemia in disease precipitation of coronary artery disease (CAD) associated type 2 diabetes mellitus (T2DM). Diabetes/metabolism research and reviews. 2015;31(7):663-71.
87. Singh G, Bhalla A, Bhatti JS, Chandel S, Rajput A, Abdullah A, et al. Potential of chitinases as a biopesticide against agriculturally harmful fungi and insects. Res Rev J Microbiol Biotechnol. 2014;3:27-32.
88. Sidhu I, Bhatti J, Bhatti G. Modulatory action of melatonin against chlorpyrifos induced hepatotoxicity in Wistar rats. Asian J Med Sci. 2014;2:123-31.
89. Bhatti G, Sidhu I, Saini N, Puar S, Singh G, Bhatti J. Ameliorative role of melatonin against cypermethrin induced hepatotoxicity and impaired antioxidant defense system in Wistar rats. IOSR J Environ Sci Toxicol Food Technol. 2014;8(1):39-48.
90. Bhatti G, Puar S, Saini N, Bhadada S, Vijayvergiya R, Mastana S, et al. Evaluation of risk factors associated with type 2 diabetes and related complications in Asian Indians: the North Indian Diabetes and Cardiovascular Disease (NIDCVD) Study-I. J Diabetes Metab. 2014;5(462):2.
91. Bhatti G, Sidhu I, Bhatti J. Protective effect of melatonin against malathion induced alterations in antioxidant defense system and morphology of erythrocytes in Wistar rats. Journal of Basic & Applied Sciences. 2013;9:438-46.
92. Bhatti J, Sidhu I, Bhatti G. Ameliorative action of melatonin on oxidative damage induced by atrazine toxicity in rat erythrocytes. Molecular and cellular biochemistry. 2011;353(1):139-49.
93. Bhatti G, Bhatti J, Kiran R, Sandhir R. Biochemical and morphological perturbations in rat erythrocytes exposed to ethion: protective effect of vitamin E. Cellular and Molecular Biology. 2011;57(1):70-9.
94. Bhatti G, Bhatti J, Kiran R, Sandhir R. Alterations in Ca2+ homeostasis and oxidative damage induced by ethion in erythrocytes of Wistar rats: ameliorative effect of vitamin E. Environmental toxicology and pharmacology. 2011;31(3):378-86.
95. Bhatti JS, Bhatti GK, Mastana SS, Ralhan S, Joshi A, Tewari R. ENPP1/PC-1 K121Q polymorphism and genetic susceptibility to type 2 diabetes in North Indians. Mol Cell Biochem. 2010;345(1-2):249-57. doi: 10.1007/s11010-010-0579-2.
96. Bhatti JS, Bhatti G, Mastana S, Ralhan S, Joshi A, Tewari R. ENPP1/PC-1 K121Q polymorphism and genetic susceptibility to type 2 diabetes in North Indians. Molecular and cellular biochemistry. 2010;345(1):249-57.
97. Bhatti JS, Bhatti GK, Joshi A, Rai S, Mastana SS, Ralhan SK, et al. Identification of the risk factors for the high prevalence of type 2 diabetes and its complications in a Punjabi population: North Indian Diabetes Study: A case-control study. International Journal of Diabetes in Developing Countries. 2007;27:108-15.
98. Sanghera DK, Bhatti JS, Bhatti GK, Ralhan SK, Wander GS, Singh JR, et al. The Khatri Sikh Diabetes Study (SDS): study design, methodology, sample collection, and initial results. Human biology. 2006:43-63.
- Ph.D Supervision: Ph.D. degrees awarded (04); Currently supervising (04)
- Master’s Dissertations: 35 (M.Sc. in Biotechnology & M.Sc. in Microbial Biotechnology); 32 (M.Sc. in Molecular Medicine)
- Nutrition and Health-Project Reports: 50 students of Diploma in Nutrition and Health Education Diploma (DNHE) program offered by Indira Gandhi National Open University (IGNOU), New Delhi India.
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Attended an International Conference on Innovations in Biotechnology and Life Sciences, 2020 (ICIBLS) |
December 18th to 20th, 2020 |
International Conference |
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“Mathematical Applications in Human Cognition and Neuroscience” hosted by the Department of Mathematics, Assam Don Bosco University, India via YouTube live. |
September 16, 2020, at 3:00 PM IST |
International Webinar |
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Bhatti JS, Kaur S, Bhadada SK, Vijayvergiya R (2019) Genetic susceptibility and oxidative damage induced by hyperglycaemia in coronary artery disease subjects. Chandigarh Science Congress-CHASCON 2019 held Panjab University Chandigarh India. (Poster presentation) |
13-15th Mar 2019 |
National Conference |
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Bhatti JS, Kaur S, Kaur N, Bhatti GK, Bhadada SK, Vijayvergiya R (2018) Glutathione-S-Transferase Gene Variants and Their Susceptibility to Type 2 Diabetes and Related Cardiovascular Complications in Asian Indians. International Conference on Science: Emerging Scenario & Future Challenges held at National Institute of Technology, Hamirpur, Himachal Pradesh in Collaboration with NIT Hamirpur & APA on 8th-9th September 2018. |
8-9th Sept 2018 |
International Conference |
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Bhatti JS, Kaur S, Vijayvergiya R, Tewari R (2018) Vitamin D receptor gene variants (BsmI, TaqI, and FokI) and their susceptibility to coronary artery disease in Asian Indians. International Conference on “Translational Research in Life Sciences” held at the Department of SAIF/CIL, Panjab University Chandigarh (Poster Presentation) |
5-7 July 2018 |
International Conference |
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Bhatti JS (2018). Attended an “International Seminar on Biosafety: Risks and Management” organized by the Department of Biochemistry Panjab University Chandigarh under DST-PURSE grant (Delegate) |
18th Mar 2018 |
International Seminar |
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Bhatti JS (2018). A resource person and delivered a lecture on “Emerging role of nanotechnology and personalized medicine in cancer” in a “National Seminar on Recent Trends in Science and Technology” organized by Guru Teg Bahadur Khalsa College for Women (Resource Person) |
7th Mar 2018 |
National Seminar |
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Bhatti JS, Sidhu IPS, Kaur S, Saini NK, Bhatti GK (2018) Biochemical and structural changes induced by atrazine intoxication in liver tissues of Wistar rats - an ameliorative action of melatonin. “CHASCON 2018” held at Panjab University Chandigarh (Poster presentation) |
12-14, Feb 2018 |
National Conference |
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Bhatti JS, Kaur S, Saini NK, Bhadada SK (2017) Genetic susceptibility of CAPN10 gene variants and risk of type 2 diabetes in Indian population. “Symposium on Novel Innovations in Biochemistry” organized by Department of Biochemistry Panjab University Chandigarh (Poster presentation) |
22-23 Dec 2017 |
University Level Symposium |
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Bhatti JS*, Sidhu IPS, Bhatti GK (2017) Ameliorative action of melatonin contrary to the biochemical changes and structural deformities induced by atrazine intoxication in erythrocytes of Wistar rats. “37th Annual Conference of Society of Toxicology (STOX 2017)” held in the Department of Pharmacology, PGIMER, Chandigarh. (Poster presentation) |
17-19 Nov 2017 |
National Conference |
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Bhatti JS*, Kaur S, Saini NK, Bhadada SK (2017) The ENPP1/PC1 K121Q polymorphism and risk of osteoporosis in type 2 diabetic subjects of North India. “13th National Congress of Indian Society for Bone and Mineral Research (ISBMR)” held at PGIMER, Chandigarh (Delegate) |
10-12 Nov 2017 |
National Conference |
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Bhatti JS*, Reddy PH (2017) Pharmacogenomics and nanotechnology - A step towards advancing personalized medicine and improved drug targeting in age-related metabolic disorders. “NanoSciTech-2017” held at Panjab University, Chandigarh (Poster presentation) |
8-10, Nov, 2017 |
International Conference |
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Bhatti JS* (2017) Genetic susceptibility of renin-angiotensin system gene variants ACE (ID), AT1R (A1166C), and AGT (M235T) to hypertension and coronary artery disease in North Indians. “27th National Conference of Indian Society of Hypertension (BPCON 2017)” held at India Habitat Centre, New Delhi (Oral presentation) |
1-3 Sept 2017 |
National Conference |
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Bhatti JS*, Saini NK, Kaur S, Bhadada SK, Vijayvergiya R, Mastana SS, Bhatti GK, Reddy PH (2017) Impact of modifiable risk factors in escalation of types 2 diabetes and related complications in Asian Indian population. “2nd International Conference on Obesity and Chronic Diseases” held at San Francisco, CA USA (Poster presentation) |
6-8, July 2017 |
International Conference |
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Bhatti JS*, Kavya TK, Reddy PH (2017) Are TALLYHO/JngJ mice, a relevant model to study type 2 diabetes, obesity, and Alzheimer’s disease? “2nd Annual Symposium of Center of Excellence for Translational Neuroscience and Therapeutics” held at Texas tech University Health Sciences Center, Lubbock TX USA (Poster No. 21) (Poster presentation) |
27th Apr 2017 |
International Symposium |
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Bhatti JS*, Kaur S, Saini NK, Tewari, R, Vijayvergiya R (2016) Q192R and L55M Polymorphisms in Paraoxonase 1 and I/D Polymorphism in Angiotensin-Converting Enzyme Genes are Associated with Coronary Artery Disease and Type 2 Diabetes in Asian Indians”. "14th World Congress on Insulin Resistance Diabetes and Cardiovascular Diseases-2016" held in Hilton, Universal City, LA, California USA (Abstract #00083) (Poster presentation) |
1-3 Dec 2016 |
International Conference |
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Bhatti JS*, Saini RK, Sanyal SN. Chemopreventive role of celecoxib and etoricoxib in DMBA induced lung carcinogenesis. “4th International conference on “Pharmacogenomics, proteomics in Drug Discovery, development and clinical Therapeutics (PPDDCT-2016)” held at Chitkara University, Rajpura in collaboration with Harvard Medical School, USA Poster presentation |
13-14 Apr 2016 |
International Conference |
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Bhatti GK, Bhatti JS, Vijayvergiya R, Singh B. Genetic variations in the susceptibility genes and risk of coronary artery disease in Asian Indians. “4th International conference on “Pharmacogenomics, proteomics in Drug Discovery, development and clinical Therapeutics" held at Chitkara University, Rajpura in collaboration with Harvard Medical School, USA (Best poster award)- Poster presentation |
13-14 Apr 2016 |
International Conference |
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Bhatti JS*, Saini NK, Bhatti GK, Puar SK, Bhadada SK. Genetic variants of calpain-10 gene and risk of type 2 diabetes in north Indian population. “5th Annual Conference of Molecular Pathology Association of India and International Symposium on “Integration of Genetics and Genomics in Laboratory Medicine” held at PGIMER, Chandigarh, India (Poster presentation) |
12-13 Mar 2016 |
International Symposium |
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Bhatti JS*, Saini RK, Sanyal SN, Chemopreventive action of NSAIDs in modulating the lipid microenvironment of type II lung pneumocytes membrane in 9, 10-dimethyl-1,2-benzanthracene induced lung carcinogenesis. “5th Annual Meeting of Indian Academy of Biomedical Sciences” held at the India Habitat Centre, New Delhi (Poster presentation) |
26-28, Feb 2016 |
National Conference |
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Bhatti JS*, Saini NK, Puar SK, Bhadada SK,Bhatti GK. Association of Insertion/Deletion polymorphism of angiotensin-I converting enzyme gene with type 2 diabetes in north Indians. “42nd National Conference of Association at Clinical Biochemists of India” held at PGIMER, Chandigarh (Poster presentation) |
25-28, Nov 2015 |
National Conference |
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Bhatti JS*, Sidhu IPS, Bhatti GK. Ameliorative action of melatonin against cypermethrin induced toxicity and impaired antioxidant defense system in the brain tissues of female Wistar rats. “Annual Conference of Indian Academy of Neurosciences- “Neuroscience Research from Mechanisms to Applications” held at Panjab University, Chandigarh (Poster presentation) |
31st Oct-2nd Nov 2015 |
National Conference |
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Bhatti JS*, Saini RK, Sanyal SN, Chemo-preventive action of non-steroidal anti-inflammatory drugs in 9, 10-dimethyl benzanthracene induced lung carcinogenesis in balb/c mice: Expression of COX-1, COX-2, and Nf-κB. “1st International Conference on Emerging Trends of Nanotechnology in Drug Discovery” University of Delhi South Campus (UDSC), India (Poster presentation) |
26-27, May 2014 |
International Conference |
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Bhatti JS*, Puar SK, Bhadada S, Bhatti GK (2012) No association of SNP 19 polymorphism of calpain 10 gene with the risk of type 2 diabetes in North Indians. “Prospects Perspectives in Biochemistry” held at Panjab University, Chandigarh, India (Poster presentation) |
10-11, Feb 2012 |
University Level Symposium |
Adhoc Reviewer of Several National and International Journals