Dr. Vinod Kumar

Contact Info
Vinod Kumar
07018660635
Department of Chemistry, Central University of Punjab Bathinda
Vinod Kumar

Associate Professor
Department of Chemistry
School of Basic Sciences

Qualification

2007- Ph.D (Organic chemistry)
• Thesis entitled “Chemical Investigations of some Bioactive Phenylethanoids and

Phenylpropanoids Employing Green Methodologies.”

Guru Nanak Dev University (GNDU) Amritsar, Punjab, India; Supervisor: Dr. Arun K Sinha, Senior Scientist, Natural Plant Products Division, I.H.B.T., CSIR, Palampur 176 061 H.P., India; Email: aksinha8@rediffmail.com

  • 2001 Bachelor of Education (B.Ed) Himachal Pradesh University, Shimla, India

  • 2000 Master of Science (Organic Chemistry) Himachal Pradesh University, Shimla, India

  • 1998 Bachelor of Science
    Subjects: Chemistry, Physics & Mathematics
    Post Graduate College Hamirpur, (H.P. University, Shimla) India

Experience
Teaching Experience

  • Assistant Professor (From June 2012 to Sept 2019)

    Department of Pharmaceutical Sciences and Natural Products, Central University of Punjab

    Bathinda, Punjab-151001

  • Professor (From Sept 2019 to Feb. 2020)

    Department of Chemistry, School of Physical and Chemical Sciences, Central University of

    South Bihar, Gaya, Bihar-824236, India.

  • Associate Professor (From Feb. 2020 to till date)

    Department of Chemistry, Central University of Punjab, Ghudda Campus, Bathinda, Punjab-151401

Research Experience

Project Assistant: (from Sept. 2003 to Dec. 2003)

Institute of Himalayan Bioresource Technology (CSIR), Palampur H.P, India. Worked on a project sponsored by Defense Research and Development Organization

Junior Research Fellow/ Senior Research Fellow: (Jan. 2004-Dec. 2007) Institute of Himalayan Bioresource Technology (I.H.B.T.), CSIR, Palampur H.P, India.

(The position was supported by University Grant Commission Delhi, Govt. of India, India) Research field: Chemical Investigations of some Bioactive Phenylethanoids and

Phenylpropanoids Employing Green Methodologies. Post doc fellow: (From Feb. 2008 to Dec. 2009)

European Research Centre for Drug Discovery and Development, Dipartimento farmaco Chimico Technologico, Universitá di Siena, Siena, Italy. Research Field: CNS active compound (antipsychotics)

Designing and synthesis of arylalkylpiperazine scafolds involving multistep protocols 

and their screening/SAR studies for antipsychotic agents.

  • Anti-tumor agents Synthesis of Benzodiazepine derivatives involving multi-step peptide synthesis and their

    screening for anti-tumor activities.

  • Research Officer (From Jan. 2010 to June 2012) Department of Pharmacy and Pharmacology, University of Bath, BA2 7AY, United Kingdom.

  • Drug Abuse Treatment (Opioid receptor ligands) Synthesis and screening of naltrexone derivatives as selective MOP/NOP agonist Synthesis and SAR studies of Buprenorphine derivatives as potential MOP, KOP antagonists/

    NOP partial agonists

Administrative Experience
Head Department of Chemistry, Central University of Punjab.

Head Department of Chemistry, Central University of South Bihar

Training and Placement officer, Central University of Punjab

Chairperson, Board of Studies, Department of Chemistry, CUPB

Member School Board, CUPB

Member Academic Council, CUPB

Any Other Experience

 

Research Area

Organic Synthesis and Medicinal Chemistry,

Research Interests

Designing, Synthesis & Evaluation of multi-targeting agents for the treatment of various neurological disorders including Alzheimer’s disease, Parkinson’s disease and depression. In my research group, compounds are being developed as inhibitors of monoamine oxidase enzyme, acetylcholine esterase enzyme and beta-amyloid to find potential drug candidates. Target compounds are being designed using molecular modeling and molecular simulation studies. The synthesized compounds are screened against enzyme-based assays to determine their multi-potent activity. 

Research Grants/Projects

Title of Projects

Year

Year to

Funding Agency

Amount

Synthesis of Bioactive Heterocyclic Scaffolds Using Novel Green Technologies.

2013

2015

UGC

6 Lakhs

Design, synthesis and evaluation of combrestatins inspired small molecules as putative tubulin polymerization inhibitors

2015

2017

CUPB (RSM)

3 Lakhs

Spatial distribution of Uranium and associated water quality parameters in groundwater/drinking water resources of South Eastern districts of Punjab (co-PI)

2016

2019

BRNS

26.97 Lakh

Targeting Cancer Stem Cells through One Drug Multi-Target Approach (microtubule inhibition, vascular disruption and anti-angiogenesis)

2016

2019

DST Extramural

30.09 Lakh

Indo-Austria joint visit grant

2017

2019

DST

9.04 Lakh

Multi-target paradigm in drug discovery efforts to combat Alzheimer’s Disease

2019

2022

CSIR

31 Lakh
Professional Affiliation

Indian Society of Chemists and Biologists: LF 818/2017

The Indian Science Congress Association: L34119

Indian Chemical Society: F/8004

Professional Recognition/Awards/Scholarships
Research Collaboration

•Dr Amit Prasad, IIT Mandi ; Dr Jyoti  Parkash, CUP Bathinda

Dr Jyoti Parkash, Department of Zoology, CUP Bathinda

•Dr Somesh Baranwal, Department of Microbilology, CUP Bathinda:

Dr Rakesh Kumar, Department of Chemistry, CUP Bathinda

Prof. Anjana Munshi, Department of Human Genetics and Molecular Medicine, CUP Bathinda

Prof. Sanjeev Thakur, Department of Botany, CUP Bathinda.

Publications
Papers
  1. Morpholine Substituted Quinazoline Derivatives as Anticancer Agents Against MCF-7, A549 and SHSY-5Y Cancer Cell Lines and Mechanistic Studies

Ashish Ranjan Dwivedi, Vijay Kumar, Vikash Prashar, Akash Verma, Naveen Kumar, Jyoti Parkashand Vinod Kumar, RSC Medicinal Chemistry, 2022, accepted

  1. Advancements in the Development of Multi-Target Directed Ligands for the Treatment of Alzheimer’s Disease

Naveen Kumar, Vijay Kumar, Piyush Anand, Vinay Kumar, Ashish Ranjan Dwivedi and Vinod Kumar; Bioorganic Medicinal Chemistry, 2022, accepted

  1. A Review on the Arylpiperazine Derivatives as Potential Therapeutics for the Treatment of Various Neurological Disorders

Bhupinder Kumar, Naveen Kumar, Amandeep Thakur, Vijay Kumar, Rakesh Kumar and Vinod Kumar; Cur. Drug Targets, 2021; accepted

  1. Investigation of Indole-3-piperazinyl derivatives as potential antidepressants: Design, synthesis, in vitro, in vivo and in silico analysis

Ravi Ranjan Kumar, Vijay Kumar, Dilpreet Kaur, Nilay Kumar Nandi, Ashish Ranjan Dwivedi, Vinod Kumar and Bhupinder Kumar; ChemistrySelect, 2021, 6, 11276-11284; Impact Factor-1.81

  1. Multi-Target-Directed Ligands as an Effective Strategy for the Treatment of Alzheimer’s Disease

Bhupinder Kumar, Amandeep Thakur, Ashish Ranjan Dwivedi, Rakesh Kumarand Vinod Kumar; Curr. Med. Chem. 2021, accepted; Impact Factor- 4.53 doi: 10.2174/0929867328666210512005508.

  1. Role of Peroxisome Proliferator-Activated Receptor gamma (PPARγ) in Different Disease States: Recent Updates

Suvadeep Mal, Ashish Ranjan Dwivedi, Vijay Kumar, Naveen Kumar, Bhupinder Kumarand Vinod Kumar; Curr. Med. Chem. 2021, 28, 3193-3215, Impact Factor- 4.53, DOI: 10.2174/0929867327666200716113136

  1. Metal-Free Multicomponent Construction of Tetrahydroisoquinoline-Indole Derivatives via in situ Generated ortho-Quinonoid Intermediate

Pavneet Kaur,Kamlesh Gurjar,Vinod Kumar, Sonali Gohit, Vijay Gupta and Rakesh Kumar, ChemistrySelect, 2020, 5, 12514-12520; Impact Factor-1.81; https://doi.org/10.1002/slct.202002802

  1. Anti-proliferative Potential of Triphenyl Substituted Pyrimidines Against MDA-MB-231, HCT-116 and HT-29 cancer cell lines

Ashish Ranjan Dwivedi, Vijay Kumar, Harmeet Kaur, Naveen Kumar, Ravi Prakash Yadav, Ramarao Poduri, Somesh Baranwaland Vinod Kumar; Bioorg. Med. Chem. Lett., 2020, 30, 127468; Impact Factor- 2.51, DOI: 10.1016/j.bmcl.2020.127468

  1. Design, Synthesis and Evaluation of O-Pentyne Substituted Diphenylpyrimidines as Monoamine Oxidase and Acetylcholinesterase Inhibitors

Vijay Kumar, Bhupinder Kumar, Ashish Ranjan Dwivedi, Devashish Mehta, Naveen Kumar, Beenu Bajaj, Tania Arora, Vikash Prashar, Jyoti Parkashand Vinod Kumar; ChemistrySelect, 2020, 5, 8021-8032, https://doi.org/10.1002/slct.202002425; Impact Factor-1.81

  1. Metal- and solvent-free multicomponent decarboxylative A3-coupling for the synthesis of propargylamines: Experimental, computational and biological investigations" Pavneet Kaur, Bhupinder Kumar, Kamlesh Gurjar, Rohtash Kumar, Vinod Kumar, Rakesh Kumar; J. Org. Chem. 2020, 85, 2231-2241. https://doi.org/10.1021/acs.joc.9b02806; Impact Factor- 4.8
  2. Recent advances in decarboxylative C-C bond formation using direct or in situ generated alkenyl acids

Pavneet Kaur, Vinod Kumar, and Rakesh Kumar; Catalysis Reviews, 2020, 62, 118161, Impact Factor- 11.0. https://doi.org/10.1080/01614940.2019.1700736

  1. Targeting Cancer Stem Cells Pathways for the Effective Treatment of Cancer

Ashish Ranjan Dwivedi, Amandeep Thakur, Vijay Kumar, Ira Skvortsova and Vinod Kumar; Cur. Drug Targets, 2020, 21, 258-278,  Impact Factor- 3.34. doi: 10.2174/1389450120666190821160730

  1. Dipropargyl Substituted Diphenylpyrimidines as Dual Inhibitors of Monoamine Oxidase and Acetylcholinesterase

Bhupinder Kumar, Vijay Kumar, Vikash Prashar, Suresh Saini, Ashish Ranjan Dwivedi, Beenu Bajaj, Devashish Mehta, Jyoti Parkash*and Vinod Kumar* Eur. J. Med. Chem. 2019, 177, 221-234. https://doi.org/10.1016/j.ejmech.2019.05.039

  1. Genomic alterations associated with HER2+ breast cancer risk and clinical outcome in response to trastuzumab

Heena Singla, Raman Preet Kaur, Gowhar Shafi, Rajesh Vashistha, Raja Paramjeet Singh Banipal, Vinod Kumar, Anjana Munshi, Molecular Biology Report, 2019, 46, 823-831. doi: 10.1007/s11033-018-4537-5

  1. 4,6-Diphenylpyrimidine Derivatives as Dual Inhibitors of Monoamine Oxidase and Acetylcholinesterase for the Treatment of Alzheimer’s Disease

Bhupinder Kumar, Ashish Ranjan Dwivedi, Bibekananda Sarkar, Sukesh Kumar Gupta, Sairam Krishnamurthy, Anil K Mantha, Jyoti Prakash, and Vinod Kumar, ACS Chemical Neuroscience, 2019, 10, 252-265. DOI: 10.1021/acschemneuro.8b00220

  1. Synthesis, biological evaluation and SAR studies of 14β‐phenylacetyl substituted 17-cyclopropylmethyl- 7,8-dihydronoroxymorphinones derivatives: Ligands with mixed NOP and opioid receptor profile

Vinod Kumar, Willma E. Polgar, Taline V Khroyan, Gerta Cami-Kobeci, Mark Thomas, Lawrence Toll, Stephen M. Husbands, Frontiers in Psychiatry, 2018, 9, 430

  1. Chitosan-supported copper as an efficient and recyclable heterogeneous catalyst for A3/decarboxylative A3-coupling reaction

Pavneet Kaur, Bhupinder Kumar, Vinod Kumar, Rakesh Kumar; Tetrahedron Letter, 2018, 59, 1986-1991. Impact Factor: 2.38

  1. Synthesis and Biological Evaluation of Pyrimidine Bridged Combretastatin Derivatives as Potential Anticancer Agents and Mechanistic Studies

Bhupinder Kumar, Praveen Sharma, Vivek Prakash Gupta, Madhu Khullar, Sandeep Singh, Nilambra Dograand Vinod Kumar; Bioorganic Chemistry, 2018, 78, 130-140. Impact Factor: 3.23

  1. Synthesis, Biological Evaluation and Molecular Modeling Studies of Phenyl-/Benzhydrylpiperazine Derivatives as Potential MAO Inhibitors

Bhupinder Kumar, Sheetal, Anil K Mantha and Vinod Kumar*, Bioorganic Chemistry, 2018, 77, 252-262. Impact Factor: 3.23

  1. Synthesis, Biological Evaluation and Molecular Modeling Studies of Propargyl Containing 2,4,6-trisubstituted Pyrimidine Derivatives as Potential anti-Parkinson agents

Bhupinder Kumar, Mohit Kumar, Ashish Ranjan Dwivedi,and Vinod Kumar*, ChemMedChem, 2018, 13, 705-712. Impact Factor: 3.23

  1. Editorial: Recent Trends in Anticancer Drug Development: Challenges and Opportunities

I.-I. Skvortsova, V. Kumar, Curr. Med. Chem. 2017, 24, 4727-4728. Impact Factor: 3.7

  1. Recent Synthetic Strategies for Monocyclic Azole Nucleus and Its Role in Drug Discovery and Development

Neha, Ashish Ranjan Dwivedi, Rakesh Kumar and Vinod Kumar*, Curr. Org. Synth., 2018, 15, 321-340. Impact Factor: 1.92

  1. Recent Advances in HER2 Positive Breast Cancer Epigenetics: Susceptibility and Therapeutic Strategies

Heena Singla, Abhilash Ludhiadch, Raman Preet Kaur, Vinod Kumar**, Anjana Munshi*, Eur. J. Med. Chem. 2017, 142, 316-327. Impact Factor: 4.5

  1. Recent Updates on the Therapeutic Potential of HER2 Inhibitors for the Treatment of Breast Cancer

Heena Singla, Anjana Munshi,* Raja Paramjit Singh Banipal and Vinod Kumar* Current Cancer Drug Targets; 2018, 18, 306-327. Impact Factor: 3.0

  1. Promising Targets in Anti-cancer Drug Development: Recent Updates

Bhupinder Kumar, Sandeep Singh, Ira Skvortsova and Vinod Kumar*, Current Medicinal Chemistry, 2017, 27, 4729-4752, Impact Factor: 3.25

  1. Role of Genomic Alterations in HER2 Positive Breast Carcinoma: Focus on Susceptibility and Trastuzumab-Therapy

Heena Singla, Sourav Kalra, Preeti Kheterpal, Vinod Kumar*, Anjana Munshi*Current Cancer Drug Targets; 2017, 17, 346-356, Impact Factor- 3.0

  1. Mechanisms of Tubulin Binding Ligands to Target Cancer Cells: Updates on Their Therapeutic Potential and Clinical Trials

        Bhupinder Kumar, Rakesh Kumar, Ira Skvortsova, and Vinod Kumar*; Current Cancer Drug Targets; 2017, 17, 357-375, Impact Factor- 3.0

  1. Recent Developments on the Structure-Activity Relationship Studies of MAO Inhibitors and Their Role in Different Neurological Disorders

Bhupinder Kumar, Sheetal, Anil K. Mantha and Vinod Kumar*; RSC Advances; 2016, 6, 42660-42683; Impact Factor- 3.84

  1. Regioselective Alkylation of 1,2,4-triazole Using Ionic Liquids Under Microwave Conditions Ramandeep Kaur, Bhupinder Kumar, Ashish Ranjan Dwivedi, Vinod Kumar*; Green Processing and Synthesis; 2016, 5, 233-237. Impact Factor- 1.15
  2. A Perspective on Monoamine Oxidase Enzyme as Drug Target: Challenges and Opportunities

Bhupinder Kumar, Vivek Prakash Gupta and Vinod Kumar*; Cur. Drug Targets, 2017, 18, 87-97;. Impact Factor- 3.34

  1. Radiation resistance: Cancer stem cells (CSCs) and their enigmatic pro-survival signaling.

Ira Skvortsova, Paul Debbage, Vinod Kumar, Sergej Skvortsov; Semin. Cancer Biol. 2015, 35, 39-44;. Impact Factor- 9.3

  1. Recent Developments on 1,2,4-Triazole Nucleus in Anticancer Compounds: A Review.

Kaur R, Dwivedi AR, Kumar B, Kumar* V; Anticancer Agents Med Chem. 2016, 16(4): 465-489,. Impact Factor- 2.5

  1. C7β-Methyl analogues of the orvinols: The discovery of kappa opioid antagonists with nociceptin/orphanin FQ peptide (NOP) receptor partial agonism and low, or zero, efficacy at mu opioid receptors

Juan Pablo Cueva , Christopher Roche , Mehrnoosh Ostovar , Vinod Kumar , Mary J Clark , Todd Hillhouse , John W. Lewis , John R. Traynor , and Stephen M Husbands; J. Med. Chem., 2015, 58, 4242-4249. Impact Factor- 5.6

  1. Pyrrolo- and Pyridomorphinans: Non-selective opioid antagonists and delta opioid agonists/mu opioid partial agonists

Vinod Kumar, M. J. Clark, J .R. Traynor, J. W. Lewis, S. M. Husbands; Bioorg. Med. Chem.  2014, 22, 4067-4072. Impact Factor-2.90 

  1. Selectively Promiscuous Opioid Ligands: Discovery of High Affinity/Low Efficacy Opioid Ligands with Substantial Nociceptin Opioid Peptide Receptor Affinity

Vinod Kumar, Irna E. Ridzwan , Konstantinos Grivas , John W. Lewis , Mary J Clark , Claire Meurice, Corina Jimenez-Gomez , Irina D. Pogozheva , Henry I. Mosberg , John R. Traynor , and Stephen M Husbands; J. Med. Chem., 2014, 57, 4049-4057. Impact Factor- 5.6

  1. Selective Kainate Receptor (GluK1) Ligands Structurally Based upon 1H‑Cyclopentapyrimidine-2,4(1H,3H)-dione: Synthesis, Molecular Modeling, and Pharmacological and Biostructural Characterization

Raminta Venskutonyt, Stefania Butini, Salvatore Sanna Coccone, Sandra Gemma, Margherita Brindisi, Vinod Kumar, Egeria Guarino, Samuele Maramai, Salvatore Valenti, Ahmad Amir, Elena Antón Valadés, Karla Frydenvang, Jette Sandholm Kastrup, Ettore Novellino, Giuseppe Campiani, and Darryl S. Pickering; J. Med. Chem., 2011, 54, 4793-4805. Impact Factor- 5.6

  1. Discovery of Bis-homo(hetero)arylpiperazines as Novel Multifunctional Ligands Targeting Dopamine D3 and Serotonin 5-HT1A and 5-HT2A Receptors

Stefania Butini, Giuseppe Campiani, Silvia Franceschini, Francesco Trotta, Vinod Kumar, Egeria Guarino, Giuseppe Borrelli, Isabella Fiorini, Ettore Novellino, Caterina Fattorusso, Marco Persico, Nausicaa Orteca, Karin Sandager-Nielsen, Thomas Amos Jacobsen, Kim Madsen, Jorgen Scheel-Kruger, and Sandra Gemma; , J. Med. Chem., 2010, 53, 4803-4807. Impact Factor- 5.6

  1. Development of Antitubercular Compounds Based on a 4-Quinolylhydrazone Scaffold. Further Structure-activity Relationship Studies

Sandra Gemma, Luisa Savini, Maria Altarelli, Pierangela Tripaldi, Luisa Chiasserini, Salvatore Sanna Coccone, Vinod Kumar, Caterina Camodeca, Giuseppe Campiani, Ettore Novellino, Sandra Clarizio, Giovanni Delogu, and Stefania Butini, Bio. Med. Chem., 2009, 17, 6063-6072. Impact Factor-2.90 

  1. Larvicidal and Structure–Activity Studies of Natural Phenylpropanoids and Their Semisynthetic Derivatives against the Tobacco Armyworm Spodoptera litura (Fab.) (Lepidoptera: Noctuidae)

Anu Bhardwaj, Dhananjay Kumar Tewary, Rakesh Kumar, Vinod Kumar, Arun Kumar Sinha, and Adarsh Shankera; Chemistry and Biodiversity, 2010, 7, 168-177. Impact Factor-1.9 

  1. Specific Targeting of Peripheral Serotonin 5-HT3 Receptors. Synthesis, Biological Investigation  and Structure-Activity Relationships

Elena Morelli, Sandra Gemma, Roberta Budriesi, Giuseppe Campiani, Ettore Novellino, Caterina Fattorusso, Bruno Catalanotti, Luisa, Salvatore Sanna Coccone, Sindu Ros, Giuseppe Borrelli, Vinod Kumar, Marco Persico, Isabella Fiorini, Vito Nacci, Pierfranco Ioan, Alberto Chiarini, Michel Hamon, Alfredo Cagnotto, Tiziana Mennini, Claudia Fracasso, Molena Colovic, Silvio Caccia, and Stefania Butini, J. Med. Chem., 2009, 52, 3548-3562. Impact Factor- 5.6

  1. Unique versatility of Ionic liquids as clean and efficient decarboxylation catalyst: A metal and quinoline free paradigm towards synthesis of Indoles, Styrenes, Stilbenes and Arene derivatives under microwave in aqueous condition

Abhishek Sharma, Rakesh Kumar, Naina Sharma, Vinod Kumar and Arun K. Sinha, Adv. Synth. Catal., 2008, 350, 2910-2920. Impact Factor-5.53 

  1. Neutral Ionic Liquid [hmim]Br as a Green Reagent and Solvent for the Mild and Efficient Dehydration of Benzyl Alcohols into (E)-Arylalkenes Under Microwave Irradiation

Rakesh Kumar, Abhishek Sharma, Naina Sharma, Vinod Kumar and Arun K. Sinha, Eur. J. Org. Chem.. 2008, 5577-5582. Impact Factor-3.34 

  1. Isolation and purification of acetylshikonin and β-acetoxyisovalerylshikonin from the cell suspension cultures of Arnebia euchroma (Royle) Johnston using rapid preparative HPLC

Nandini Sharma, Upendra K. Sharma, Sonia Malik,  Shashi Bhushan,Vinod Kumar, Subash C. Verma, Naina Sharma, Madhu Sharma, Arun K. Sinha J. Sep. Sci. 2008, 31, 629-635. Impact Factor-2.6 

  1. RP-HPTLC densitometricdetermination and validation of vanillin and related phenolic compounds in accelerated solvent extract of Vanilla planifolia

Upendra K. Sharma, Nandini Sharma, Ajai P. Gupta, Vinod Kumar, Arun K. Sinha J. Sep. Sci. 2007, 30, 3174-3180. Impact Factor-2.6 

  1. An Unusual, Mild and Convenient One Pot Two Step Access to (E)-Stilbenes from Hydroxy Substituted Benzaldehydes and Phenylacetic Acids Under Microwave Activation: Revelation of a New Facet on the Classical Perkin Reaction

Arun K. Sinha, Vinod Kumar, Abhishek Sharma, Anuj Sharma and Rakesh Kumar Tetrahedron, 2007, 63, 11070-11077. Impact Factor-2.80

  1. DDQ catalyzed benzylic acetoxylation of arylalkanes: A case of exquisitely controlled oxidation under sonochemical activation

Vinod Kumar, Abhishek Sharma, Meenakshi Sharma, Upendra Sharma and Arun K. Sinha, Tetrahedron, 2007, 63, 9718-9723. Impact Factor-2.80

  1. Remarkable Synergism in Methylimidazole-Promoted Decarboxylation of Substituted Cinnamic acids in basic water medium under Microwave Irradiation: A Clean Synthesis of Hydroxylated (E)-Stilbenes

Vinod Kumar, Abhishek Sharma, Anuj Sharma and Arun K. Sinha, Tetrahedron, 2007, 63, 7640-7646. Impact Factor-2.80

  1. Microwave-assisted Mild Conversion of Natural Dihydrotagetone into 5-Isobutyl-3-methyl-4,5-dihydro-2(3H)-furanone: an Analogue of Whisky Lactone         Arun K. Sinha, Bhupender P. Joshi, Anuj Sharma, Vinod Kumar and Ruchi Acharya, Aust. J. Chem., 2007, 60, 124-127. Impact Factor-1.87
  1. An Efficient Chemoselective Strategy for the Preparation of (E) -Cinnamic Esters from Cinnamaldehydes Using Heterogeneous Catalyst and DDQ

Arun K Sinha, Anuj Sharma, Anand Swaroop and Vinod Kumar, Tetrahedron, 2007, 63, 1000-1007. Impact Factor-2.80

  1. Solid-supported Green Synthesis of Substituted Hydrocinnamic Esters by Focused Microwave Irradiation

Vinod Kumar, Anuj Sharma and Arun K Sinha, Helv. Chim. Acta, 2006, 89, 483-495. Impact Factor-1.38

  1. A Chemoselective Hydrogenation of the Olefinic Bond of a, b-Unsaturated Carbonyl Compounds in Aqueous Medium Under Microwave Irradiation Anuj Sharma, Vinod Kumar and A. K Sinha, Adv. Synth. Catal., 2006, 348, 354-360. Impact Factor-5.53
  2. A Microwave-Accelerated Esterification of a, b-Unsaturated Acids with Alkyl or Aryl Carbonochloridate and Triethylamine in Acetonitrile as a Novel Esterifying Reagent Mixture Vinod Kumar, Anuj Sharma and Arun K. Sinha, Helv. Chim. Acta, 2005, 88, 811-816. Impact Factor-1.38
Research Guidance

Phd Students: Thesis awarded = 3; Pursuing = 5.

Master Thesis guided = 24

Conference/ Workshops/Seminars Attended
University Level
3
National
10
International

6

Conference/ Workshops/Seminars Organised
National Level
3
International Level

1

Peer Recognition

Editor

Current Indian Science Medicinal Chemistry

Member of Editorial Board

Current Organic chemistry  impact factor 2.01

Current Molecular Pharmacology   impact factor 3.85

Guest Editor

Current Medicinal Chemistry   impact factor 4.7

Frontiers in Oncology                   impact factor 5.74

 

 

Invited Talks/ Resource Person
Chaired two sessions in ATAL Sponsored national FDP program on “Molecular manufacturing’ from 23-27th November, 2020 in the Department of Chemistry, Central University of Punjab, Bathinda.
Delivered a lecture on “Neurological Disorders and Multi-target Directed Ligand Strategies” in a refresher course entitled ‘Chemistry: The Central Science’ organized by Department of Chemistry, UGC-HRDC, Kurukshetra held in Kurukshetra University, Kurukshetra from 05-October-2020 to 17-October-2020.
Delivered a lecturer on “Multi-target-Directed Ligands as an Effective Strategy for the Treatment of Complex Neurological Disorders” in an AICTE sponsored 6-Days online STTP on Target Based Drug Design Strategies Utilizing CADD Tools and Ecofriendly Microwave Assisted Green Synthesis” organized by ISF College of Pharmacy, Moga, Punjab, from 18th – 23rd March, 2020.

Delivered a lecturer on “Multi-potent N-Hetrocyclics for the Treatment of Neurological Disorders” in a National Symposium on Contemporary Facets in Organic Synthesis-2017 held at Indian Institute of Technology, Roorkee. Dec. 22-24, 2017.

Delivered invited talk entitled “Multi-target paradigm in drug discovery efforts” in the Department of Therapeutic Radiology and Oncology, Innsbruck Medical University, Anichstr. 35, A-6020 Innsbruck, Austria; November 28, 2017.

Delivered a lecturer on “Ionic Liquids and Inorganic Solid Support as Green Alternatives to the Volatile Organic Solvents” in a National Seminar on “Chemistry for Better Tomorrow: Current Trends and Challenges” at Postgraduate Department of Chemistry, Mata Gujri College Shri Fatehgarh Sahib March 8, 2014.
Patent Filed/ Published
PATENT FILED
  1. Single Step Process for the Direct Preparation of Aromatic Amines from Aromatic Halides and Azides; Application number 201911006109
PATENT PUBLISHED

A green process for the preparation of substituted cinnamic esters with trans- selectivity; Sinha; A K, Sharma; A, Swaroop; A, Kumar; V (US 7,741,508, Jun. 2010)

2.     A single step microwave induced process for the preparation of substituted stilbenes and its analogs; Sinha; A. K., Kumar; V and Sharma; A, (US20070276172 A1, WO2007110883 (A1) JP2009531421) (Nov. 29, 2007) 

3.         A Microwave Induced one Pot Process for the Preparation of Arylethenes; Sinha; A. K., Kumar; V and Sharma; A, (US 7,759,527, Jul 2010)

4.       Pyrimidine Bridged Biaryl Derivatives as Multi-Targeting Agents for the Treatment of Neurological Disorders; Patent number 396086 (May 4, 2022)

Contribution Towards Institutional Building
Founding faculty of the Centre for Chemical and Pharmaceutical Sciences
Established new laboratories in the newly established Department
Prepared curriculum and syllabus for the MSc and PhD programs
Purchase of sophisticated instruments for the Department
Citations